A biopsy of the brain in a patient with Progressive Multifocal Leukoencephalopathy (PML) shows viral inclusions in which cell type?
Show answer and explanation
Correct answer: Oligodendrocytes
PML is caused by the JC polyomavirus, which selectively infects and destroys oligodendrocytes in immunocompromised patients. This leads to the characteristic patchy demyelination of the central nervous system.
Keep practicing
More Viral Infections questions
- Which virus is the leading cause of 'Councilman bodies' (acidophilic bodies) in the liver?
- Which characteristic feature distinguishes Herpes Simplex Virus (HSV) vesicles from other viral skin lesions?
- What is the molecular mechanism behind 'Antigenic Shift' in Influenza A viruses?
- In HIV infection, the depletion of which cell type is the primary driver of immunodeficiency?
- Which viral infection is associated with the formation of 'Guarnieri bodies' in the cytoplasm of epithelial cells?
- Which tumor is most strongly associated with Human T-cell Lymphotropic Virus-1 (HTLV-1)?