Which characteristic feature distinguishes Herpes Simplex Virus (HSV) vesicles from other viral skin lesions?
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Correct answer: Multinucleated giant cells with nuclear molding
HSV-infected cells show 'the 3 Ms': Multinucleation, Margination of chromatin, and Molding of nuclei. Tzanck smears of the vesicle fluid are often used to identify these multinucleated cells quickly.
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