Koilocytic atypia, characterized by nuclear enlargement and perinuclear cytoplasmic vacuolization, is a hallmark of which virus?
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Correct answer: Human Papillomavirus (HPV)
Koilocytes are squamous cells showing the cytopathic effects of HPV. The virus alters the cytoskeleton, leading to a prominent 'halo' around an enlarged, hyperchromatic, 'raisin-like' nucleus.
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