Which of the following is a hallmark of 'Mixed Connective Tissue Disease' (MCTD)?
Show answer and explanation
Correct answer: High titers of anti-U1 RNP antibodies
MCTD is a clinical 'overlap' syndrome with features of SLE, systemic sclerosis, and polymyositis. A high titer of anti-U1 RNP is the defining serological characteristic.
Keep practicing
More Autoimmune Diseases questions
- Which autoimmune disease is associated with 'heliotrope rash' and 'Gottron papules'?
- Anti-Jo-1 antibodies are most commonly found in patients with which condition?
- What is the primary immunological defect in the development of Type 1 Diabetes Mellitus?
- Antiphospholipid Syndrome (APS) can occur in SLE patients and is characterized by which clinical triad?
- Which HLA alleles are most strongly associated with Systemic Lupus Erythematosus?
- The presence of 'Aschoff bodies' is specific to which autoimmune-related condition?