C. elegans was a critical model for studying apoptosis. Which gene in C. elegans is functionally homologous to the human Bcl-2?
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Correct answer: ced-9
In the nematode C. elegans, ced-9 encodes a protein that inhibits cell death, functioning similarly to the human Bcl-2 protein. Loss-of-function mutations in ced-9 lead to excessive cell death during development.
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More Apoptosis and Its Significance questions
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