What is the role of IAPs (Inhibitor of Apoptosis Proteins) in the cell?
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Correct answer: They bind and inhibit active caspases
IAPs are a group of proteins that can directly bind to and inhibit both initiator and executioner caspases. This provides a final layer of regulation to prevent accidental cell death.
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More Apoptosis and Its Significance questions
- Which of the following triggers would most likely activate the intrinsic apoptotic pathway?
- The cleavage of which structural protein by caspases leads to the characteristic 'blebbing' of the plasma membrane?
- What is the biological significance of apoptosis in the context of viral infections?
- Which of the following describes the morphological hallmark of apoptosis that distinguishes it from necrosis?
- The 'intrinsic pathway' of apoptosis is primarily regulated by which organelle?
- Which family of proteins acts as the primary 'molecular switch' to either promote or inhibit apoptosis?