Apoptosis and Its Significance · NCERT Biology

The cleavage of which structural protein by caspases leads to the characteristic 'blebbing' of the plasma membrane?

  1. Hemoglobin (the oxygen-carrying protein)
  2. Ribosomal RNA (within the ribosomes)
  3. Nuclear lamins and cytoskeletal actin
  4. Mitochondrial DNA (in the matrix)
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Correct answer: Nuclear lamins and cytoskeletal actin

Caspases target the cytoskeleton and nuclear lamins for degradation. The breakdown of these structural supports causes the cell to lose its shape and develop the protrusions known as blebs.

Difficulty: Medium Question 19 of 20

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