Tissue Preparation · Histology

What is the purpose of the 'water bath' in the histology laboratory?

  1. To wash the fixative off the tissue
  2. To keep the microtome blade cool
  3. To fully rehydrate the tissue specimen before paraffin embedding
  4. To allow the thin paraffin sections to flatten and expand
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Correct answer: To allow the thin paraffin sections to flatten and expand

Paraffin sections usually wrinkle or compress when cut. Floating them on a warm water bath (5 to 10 degrees below the melting point of the wax) allows surface tension to pull the section flat before it is collected onto a slide.

Difficulty: Medium Question 15 of 20

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