Which of the following describes the function of the CTD (C-terminal domain) of RNA polymerase II?
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Correct answer: It coordinates RNA processing by recruiting capping and splicing factors
The CTD of RNA Pol II contains multiple heptapeptide repeats (YSPTSPS) that are progressively phosphorylated during transcription. Phosphorylated CTD acts as a scaffold to recruit 5' capping enzymes, splicing factors, and 3' processing machinery, coupling transcription with mRNA processing.
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