Transcription and RNA Processing · Zoology

Post-transcriptional modifications are unique to eukaryotes because:

  1. Prokaryotes lack RNA polymerase entirely
  2. Prokaryotic transcription and translation are coupled
  3. Prokaryotic genes contain no adenine nucleotides
  4. Prokaryotes have no ribosomes for translation
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Correct answer: Prokaryotic transcription and translation are coupled

In prokaryotes, the absence of a nuclear envelope means ribosomes can attach to and translate mRNA while it is still being transcribed — a process called coupled transcription-translation. This leaves no opportunity for the extensive post-transcriptional processing (capping, splicing, polyadenylation) seen in eukaryotes.

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