Transcription and RNA Processing · Zoology

Which molecules facilitate the export of mature mRNA from the nucleus to the cytoplasm?

  1. Importins and the nuclear lamina complex
  2. Exportins and the nuclear pore complex
  3. DNA polymerase and associated repair factors
  4. Sigma factors and core RNA polymerase
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Correct answer: Exportins and the nuclear pore complex

Only fully processed, mature mRNA associated with specific export proteins (like TAP/NXF1) is permitted to pass through the nuclear pore complex. This serves as a quality control mechanism to ensure defective transcripts are not translated.

Difficulty: Medium Question 19 of 20

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