Transcription and RNA Processing · Zoology

What is the biological significance of mRNA capping?

  1. It marks the site where transcription terminates
  2. It retains the mRNA within the nucleus for processing
  3. It protects mRNA and promotes ribosome recognition
  4. It is required for initiating chromosomal DNA replication
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Correct answer: It protects mRNA and promotes ribosome recognition

The 5' 7-methylguanosine cap protects mRNA from exonuclease degradation and is recognized by the Cap-Binding Complex (CBC) in the nucleus and eIF4E in the cytoplasm. This cap is essential for efficient ribosome binding and translation initiation.

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