Which family of proteins acts as the primary 'molecular switch' to either promote or inhibit apoptosis?
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Correct answer: Bcl-2 protein family
The Bcl-2 family contains both pro-apoptotic (e.g., Bax, Bak) and anti-apoptotic (e.g., Bcl-2, Bcl-xL) members. The ratio and interaction between these proteins determine whether the cell will initiate the apoptotic program.
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