Which phospholipid moves from the inner to the outer leaflet of the plasma membrane, acting as an 'eat-me' signal for phagocytes?
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Correct answer: Phosphatidylserine
In healthy cells, phosphatidylserine is restricted to the inner leaflet of the plasma membrane. During apoptosis, it flips to the outer leaflet, allowing macrophages to recognize and engulf the cell without inducing inflammation.
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