Which lesion is most characteristic of a myocardial infarction (MI) on gross pathology, 24 hours after onset?
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Correct answer: Dark mottling of subendocardial region
On the standard gross (Robbins) timeline, dark mottling of the infarcted myocardium appears at roughly 12-24 hours after onset. A pale, yellow-tan softened appearance develops later, at about 1-3 days, becoming maximal by 7-10 days, and a grey-white scar forms over weeks to months. Hypereosinophilic contraction-band change is a microscopic finding, not a gross one, so it does not fit a gross-pathology question.
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