Which glomerular disease is most likely in a patient with systemic lupus erythematosus showing “wire-loop” lesions on light microscopy?
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Correct answer: Diffuse proliferative glomerulonephritis
Diffuse proliferative glomerulonephritis (DPGN) — often seen in SLE — shows thickened capillary walls and subendothelial immune-complex deposition, producing the characteristic “wire-loop” appearance. (Glomerular disease pathology)
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