Cell injury and death · USMLE Step 1

A patient with autoimmune vasculitis shows fibrinoid necrosis in the vessel walls. What causes this appearance?

  1. Lipid accumulation in the wall
  2. Immune complex deposition
  3. Calcium salt precipitation
  4. Fat saponification by lipase
Show answer and explanation

Correct answer: Immune complex deposition

Fibrinoid necrosis results from immune complex deposition and plasma protein leakage into vessel walls.

Difficulty: Medium Question 14 of 20

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