Cell injury and death · USMLE Step 1

A patient with reperfusion injury shows increased free radical production. Which enzyme system contributes to this?

  1. Xanthine oxidase
  2. Cytochrome oxidase
  3. Hexokinase
  4. Na+/K+ ATPase
Show answer and explanation

Correct answer: Xanthine oxidase

Reperfusion activates xanthine oxidase, generating reactive oxygen species that damage tissues.

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