Cell injury and death · USMLE Step 1

A patient with chronic inflammation demonstrates lipofuscin accumulation. What does this pigment represent?

  1. Oxidized lipid residues
  2. Iron overload in tissue
  3. Abnormal protein accumulation
  4. Excess glycogen storage
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Correct answer: Oxidized lipid residues

Lipofuscin accumulates due to wear-and-tear oxidation of lipids and is seen in aging cells.

Difficulty: Medium Question 17 of 20

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