Cell injury and death · USMLE Step 1

Cells undergoing necrosis release inflammatory signals. Which feature distinguishes necrosis from apoptosis?

  1. Cell shrinkage
  2. Formation of apoptotic bodies
  3. Loss of membrane integrity
  4. DNA laddering
Show answer and explanation

Correct answer: Loss of membrane integrity

Necrotic cells lose membrane integrity, causing inflammation, unlike apoptosis which preserves membranes.

Difficulty: Medium Question 19 of 20

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