Rotavirus infection causes severe diarrhea by which mechanism?
Show answer and explanation
Correct answer: NSP4-mediated chloride loss
Rotavirus NSP4 acts as an enterotoxin causing chloride and water loss. It also causes villous shortening.
Keep practicing
More Viruses: Life Cycle and Disease questions
- Herpes simplex virus remains latent in which location?
- A man develops severe watery diarrhea after a cruise. Stool PCR detects Norovirus. What is the genome of this virus?
- A patient with roseola (HHV-6) presents with high fever followed by a rash. Which cells does the virus primarily infect?
- A man returns from Africa with hemorrhagic fever caused by Ebola virus. To which viral family does Ebola belong?
- A newborn exposed to rubella in utero develops congenital cataracts. What property of rubella enables transplacental infection?
- A patient with hepatitis B shows ground-glass hepatocytes. Which component of HBV accumulates in hepatocytes?