A patient infected with HPV-16 develops cervical intraepithelial neoplasia. Which viral proteins inactivate tumor suppressors?
Show answer and explanation
Correct answer: E6 and E7
HPV E6 inhibits p53 and E7 inhibits Rb, promoting uncontrolled cell division and carcinogenesis.
Keep practicing
More Viruses: Life Cycle and Disease questions
- Rotavirus infection causes severe diarrhea by which mechanism?
- Herpes simplex virus remains latent in which location?
- A man develops severe watery diarrhea after a cruise. Stool PCR detects Norovirus. What is the genome of this virus?
- A patient with roseola (HHV-6) presents with high fever followed by a rash. Which cells does the virus primarily infect?
- A man returns from Africa with hemorrhagic fever caused by Ebola virus. To which viral family does Ebola belong?
- A newborn exposed to rubella in utero develops congenital cataracts. What property of rubella enables transplacental infection?