Viruses: Life Cycle and Disease · USMLE Step 1

A patient with roseola (HHV-6) presents with high fever followed by a rash. Which cells does the virus primarily infect?

  1. Neutrophils
  2. CD4+ T cells
  3. Hepatocytes
  4. Endothelial cells
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Correct answer: CD4+ T cells

HHV-6 infects CD4+ T cells. It causes exanthem subitum (roseola) in infants.

Difficulty: Medium Question 13 of 20

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