Host immune response · USMLE Step 1

Which cell type presents antigen on MHC II molecules to CD4+ T cells?

  1. All nucleated cells
  2. Macrophages
  3. Hepatocytes
  4. Erythrocytes
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Correct answer: Macrophages

Macrophages and other APCs express MHC II. They present extracellular antigens to CD4+ T cells.

Difficulty: Medium Question 18 of 20

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