Host immune response · USMLE Step 1

A patient vaccinated with a live attenuated virus develops long-lasting immunity. What is a key advantage of live vaccines?

  1. They require repeated booster doses for protection
  2. They stimulate only short-lived humoral immunity
  3. They induce strong cellular and mucosal immunity
  4. They cannot cause disease in immunocompromised hosts
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Correct answer: They induce strong cellular and mucosal immunity

Live vaccines mimic natural infection and stimulate robust cellular, humoral, and mucosal immunity. This leads to long-lasting protection.

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