Host immune response · USMLE Step 1

A patient develops fever and neutrophilia during acute bacterial infection. Which cytokine is primarily responsible for neutrophil recruitment?

  1. IL-2
  2. IL-8
  3. IL-4
  4. TNF-beta
Show answer and explanation

Correct answer: IL-8

IL-8 is a chemokine that attracts and activates neutrophils. It plays a key role in acute inflammation and bacterial clearance.

Difficulty: Medium Question 3 of 20

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