Host immune response · USMLE Step 1

A patient with helminth infection shows elevated IL-5. Which function does IL-5 primarily support?

  1. Macrophage activation and killing
  2. Eosinophil growth
  3. Th1 lymphocyte differentiation
  4. NK cell inhibition
Show answer and explanation

Correct answer: Eosinophil growth

IL-5 is essential for eosinophil maturation and activation. Eosinophils help kill parasites via toxic granule release.

Difficulty: Medium Question 19 of 20

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