Ultrastructure of cells · USMLE Step 1

Which ultrastructural region of a eukaryotic cell is continuous with the perinuclear space and forms an extensive network throughout the cytoplasm?

  1. Golgi cisternae
  2. Mitochondrial matrix
  3. Endoplasmic reticulum
  4. Lysosomal lumen
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Correct answer: Endoplasmic reticulum

The endoplasmic reticulum (ER) is continuous with the perinuclear space of the nuclear envelope and extends throughout the cytoplasm as a network of tubules and cisternae — visible clearly under electron microscopy.

Difficulty: Medium Question 19 of 21

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