Ultrastructure of cells · USMLE Step 1

In electron micrographs, which cellular structure appears as a system of flattened membrane-bound sacs (cisternae) typically located near the nucleus and involved in protein modification and sorting?

  1. Lysosome
  2. Golgi apparatus
  3. Peroxisome
  4. Mitochondrion
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Correct answer: Golgi apparatus

The Golgi apparatus appears as stacks of flattened cisternae in TEM images; it receives proteins from the ER, modifies and packages them into vesicles for secretion or delivery to other organelles.

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