Ultrastructure of cells · USMLE Step 1

Which ultrastructural organelle is primarily responsible for cellular degradation of worn-out organelles and macromolecules, visible as membrane-bound vesicles in EM images?

  1. Golgi apparatus
  2. Smooth endoplasmic reticulum
  3. Lysosomes
  4. Mitochondria
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Correct answer: Lysosomes

Lysosomes are membrane-bound vesicles containing hydrolytic enzymes; in EM they appear as dense bodies and are responsible for intracellular digestion and recycling of cell components.

Difficulty: Medium Question 12 of 21

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