Cytoskeleton and motility · USMLE Step 1

Which motor protein moves cargo toward the minus end of microtubules — i.e., toward the cell center (centrosome)?

  1. Kinesin
  2. Myosin II
  3. Dynein
  4. Actin-dependent ATPase
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Correct answer: Dynein

Cytoplasmic dynein is a microtubule motor protein that moves cargo toward the minus end of microtubules (toward the centrosome), while kinesin typically moves toward the plus end.

Difficulty: Medium Question 7 of 21

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