Cytoskeleton and motility · USMLE Step 1

Which cytoskeletal filament is least dynamic (i.e., most stable) under normal conditions, contributing to long-term structural integrity of tissues?

  1. Actin microfilaments
  2. Intermediate filaments
  3. Microtubules
  4. Actin stress fibers
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Correct answer: Intermediate filaments

Intermediate filaments are less dynamic compared to actin filaments or microtubules; they are stable and provide durable structural support and resistance to mechanical stress.

Difficulty: Medium Question 8 of 21

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