Cytoskeleton and motility · USMLE Step 1

Which cytoskeletal element is most important for maintaining tensile strength and anchoring organelles, rather than rapid remodeling like microfilaments or microtubules?

  1. Microtubules
  2. Intermediate filaments
  3. Actin microfilaments
  4. Myosin thick filaments
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Correct answer: Intermediate filaments

Intermediate filaments provide mechanical stability, resist tension, and help anchor organelles and the nucleus — functions that require structural support rather than dynamic remodeling.

Difficulty: Medium Question 4 of 21

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