A rare autosomal recessive disorder affects 1 in 40,000 individuals. What is the approximate allele frequency of the mutant allele?
Show answer and explanation
Correct answer: 1/200
If q² = 1/40,000, q = 1/200. This is the mutant allele frequency in the population. The value reflects the square root of the disease prevalence.
Keep practicing
More Population genetics questions
- Inbreeding in a population is most likely to increase the frequency of which of the following?
- A population experiences a sudden reduction in size due to natural disaster. Which population genetics concept best describes the resulting…
- A small group leaves a large population and establishes a new isolated community. After generations, a previously rare allele becomes more…
- If p = 0.7 in a Hardy-Weinberg population, what is the expected heterozygote frequency?
- Which of the following violates the Hardy-Weinberg assumption of random mating?
- Migration of individuals between populations results in which genetic effect?