What is “cascade screening” in the context of hereditary disorders and genetic counseling?
Show answer and explanation
Correct answer: Testing first-degree relatives of a proband with a known variant
Cascade screening involves offering genetic testing to close biological relatives of an individual (proband) known to carry a pathogenic variant, to identify carriers or at-risk individuals early.
Keep practicing
More Genetic Testing and Counseling questions
- Which of the following is a limitation of genetic counseling services globally, despite increasing demand?
- During pre-test genetic counseling, why must the possibility of incidental (secondary) findings be discussed?
- What is the primary purpose of genetic counseling before genetic testing?
- Which professional is typically qualified to provide formal genetic counseling services?
- Which of the following situations would most strongly indicate a referral for genetic counseling and possibly genetic testing?
- Which ethical principle is emphasized in genetic counseling to ensure that patients’ personal values and autonomy are respected?