Which enzyme regulates the reciprocal control between glycolysis and gluconeogenesis via modification of fructose-2,6-bisphosphate levels in liver?
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Correct answer: To prevent a wasteful, ATP-consuming futile cycle
The bifunctional enzyme that acts as PFK-2 and FBPase-2 regulates levels of fructose-2,6-bisphosphate — a potent activator of glycolysis and inhibitor of gluconeogenesis — thus coordinating the two pathways.
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