Drug Overdose Management · Pharmacology

For a patient with a life-threatening Lithium overdose and a serum level > 4 mEq/L, what is the treatment of choice?

  1. Whole bowel irrigation
  2. Emergent hemodialysis
  3. Sodium Polystyrene Sulfonate
  4. Forced diuresis
Show answer and explanation

Correct answer: Emergent hemodialysis

Lithium is a small, water-soluble molecule with a low volume of distribution, making it highly amenable to removal via hemodialysis. This is indicated in severe toxicity or when renal function is impaired.

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