In the case of Ethylene Glycol or Methanol poisoning, why is Fomepizole administered?
Show answer and explanation
Correct answer: It inhibits the enzyme Alcohol Dehydrogenase (ADH)
Fomepizole inhibits alcohol dehydrogenase, the enzyme responsible for converting ethylene glycol and methanol into toxic metabolites like oxalic acid and formic acid. This prevents systemic acidosis and end-organ damage.
Keep practicing
More Drug Overdose Management questions
- Which treatment is indicated for a patient presenting with Beta-blocker overdose and refractory bradycardia?
- Activated charcoal is most effective when administered within what time frame following drug ingestion?
- Which antidote is used to treat Iron poisoning by chelating free iron in the plasma?
- A patient with Organophosphate poisoning exhibits excessive salivation, lacrimation, and bronchospasm. Which agent specifically reverses th…
- Sodium Bicarbonate is used in Tricyclic Antidepressant (TCA) overdose primarily to:
- What is the primary risk associated with the administration of Physostigmine in an undifferentiated overdose?