Drug Overdose Management · Pharmacology

Which treatment is indicated for a patient presenting with Beta-blocker overdose and refractory bradycardia?

  1. High-dose Glucagon
  2. Sodium Bicarbonate
  3. Acetylcysteine
  4. Repeat doses of atropine
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Correct answer: High-dose Glucagon

Glucagon stimulates adenylate cyclase via a pathway that is independent of beta-receptors. This increases intracellular cAMP levels, which enhances heart rate and myocardial contractility.

Difficulty: Medium Question 6 of 20

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