A patient overdosed on Warfarin and has an INR of 12.0 with active bleeding. Which treatment provides the most rapid reversal of the anticoagulant effect?
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Correct answer: Prothrombin Complex Concentrate
While Vitamin K is necessary for the long-term production of new factors, PCC (or Fresh Frozen Plasma) provides immediate replacement of the missing Vitamin K-dependent clotting factors to stop the bleeding.
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