Which of the following is a potential cardiac side effect of Beta-2 agonists, especially at high doses?
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Correct answer: Tachycardia
At high doses Beta-2 agonists lose selectivity and stimulate cardiac Beta-1 receptors. Beta-2 mediated vasodilation also triggers a reflex tachycardia. Bradycardia and heart block are effects of beta-blockade, not beta-agonism, and blood pressure tends to fall rather than rise.
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