Which pH disturbance is typically associated with the use of thiazide diuretics?
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Correct answer: Metabolic alkalosis
Like loop diuretics, thiazides cause hypokalaemic metabolic alkalosis. This is due to volume contraction and increased H+ secretion in the distal tubule as the body attempts to reabsorb sodium in exchange for potassium and hydrogen.
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More Thiazide Diuretics questions
- In the context of bone health, thiazides are associated with which of the following?
- Which of the following is the most appropriate initial management for a patient on thiazide therapy who develops symptomatic hypokalemia?
- What is the primary molecular target inhibited by thiazide diuretics in the nephron?
- In which segment of the renal tubule do thiazide diuretics exert their primary effect?
- Which of the following electrolyte changes is a characteristic side effect of thiazide diuretics, distinguishing them from loop diuretics?
- Why are thiazide diuretics considered less effective in patients with a Glomerular Filtration Rate (GFR) below 30 mL/min?