H2 Blockers · Pharmacology

Which statement regarding the use of H2RAs in pregnancy is most accurate?

  1. They are strictly contraindicated in all trimesters
  2. They are generally safe but used only when needed
  3. They are known to cause fetal limb defects
  4. They must always be given with an antibiotic
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Correct answer: They are generally safe but used only when needed

H2RAs like Famotidine are often used for pregnancy-related heartburn when lifestyle changes and antacids fail. They cross the placenta but have not been linked to teratogenic effects in humans.

Difficulty: Medium Question 15 of 20

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