H2 blockers are frequently used in hospitalized patients primarily to prevent which condition?
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Correct answer: Stress-related mucosal damage
Critically ill patients are at risk for stress ulcers due to reduced mucosal blood flow. Prophylactic H2RAs (or PPIs) are used to maintain a higher gastric pH and prevent gastrointestinal bleeding in these high-risk settings.
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More H2 Blockers questions
- What is the primary mechanism of action of H2-receptor antagonists (H2RAs)?
- Which of the following H2 blockers is well known for inhibiting multiple Cytochrome P450 (CYP) enzymes, leading to many drug interactions?
- Which H2 blocker is associated with anti-androgenic side effects, such as gynecomastia and impotence in men?
- Compared to Proton Pump Inhibitors (PPIs), H2 blockers are generally considered:
- A patient develops 'tachyphylaxis' within 2–6 days of starting an H2 blocker. What does this term imply in this context?
- Which H2-receptor antagonist has the highest potency and the longest duration of action among the following?