In the management of an acute allergic reaction (anaphylaxis), H2 blockers are sometimes used as adjunctive therapy because:
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Correct answer: They block H2 receptors on skin blood vessels
In addition to H1 receptors, H2 receptors are involved in histamine-mediated vasodilation. Combining an H1 blocker (like diphenhydramine) with an H2 blocker (like famotidine) can be more effective for skin symptoms like hives.
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More H2 Blockers questions
- What happens to gastric pH after a single dose of an H2 blocker?
- Which of the following describes the 'acid rebound' phenomenon associated with H2RAs?
- H2 blockers are frequently used in hospitalized patients primarily to prevent which condition?
- What is the primary mechanism of action of H2-receptor antagonists (H2RAs)?
- Which of the following H2 blockers is well known for inhibiting multiple Cytochrome P450 (CYP) enzymes, leading to many drug interactions?
- Which H2 blocker is associated with anti-androgenic side effects, such as gynecomastia and impotence in men?