Genetic testing for which marker is recommended to avoid hypersensitivity to Carbamazepine in patients of European descent, as an alternative to HLA-B*15:02?
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Correct answer: HLA-A*31:01
While HLA-B*15:02 is specific to Asian populations, HLA-A*31:01 has been identified as a risk factor for carbamazepine-induced hypersensitivity reactions (including DRESS syndrome) in patients of European and Japanese descent.
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