Clinical Trials · Pharmacology

What is the primary objective of a Phase III clinical trial?

  1. To assess pharmacokinetics in patients with renal failure
  2. To compare the new drug against the current standard of care or placebo in a large population
  3. To identify the chemical structure of the drug metabolites
  4. To perform high-throughput screening of lead compounds
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Correct answer: To compare the new drug against the current standard of care or placebo in a large population

Phase III trials are large, randomized, controlled studies designed to confirm the efficacy and safety of a drug in a diverse population. Data from these trials are typically the basis for regulatory approval (NDA).

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