Clinical Trials · Pharmacology

An 'Intent-to-Treat' (ITT) analysis is used in clinical trials to:

  1. Include only the participants who strictly adhered to the study protocol
  2. Analyze data based on the treatment group participants were originally assigned to, regardless of compliance
  3. Exclude patients who experienced side effects during the trial
  4. Ensure that only the most promising results are published
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Correct answer: Analyze data based on the treatment group participants were originally assigned to, regardless of compliance

ITT analysis preserves the benefits of randomization and prevents bias caused by the loss of participants (attrition). It provides a more 'real-world' estimate of a drug's effectiveness including non-compliant patients.

Difficulty: Medium Question 8 of 20

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