Clinical Trials · Pharmacology

Which regulatory document must be submitted to the FDA before a drug can begin Phase I human testing?

  1. New Drug Application (NDA)
  2. Investigational New Drug (IND) application
  3. Abbreviated New Drug Application (ANDA)
  4. Drug Master File (DMF)
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Correct answer: Investigational New Drug (IND) application

An IND application includes preclinical data, chemical composition, and the proposed human trial protocol. Once the FDA reviews and allows the IND, the company can proceed with clinical trials.

Difficulty: Medium Question 9 of 20

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