Which sedative-hypnotic is a melatonin receptor agonist used specifically for the treatment of sleep-onset insomnia?
Show answer and explanation
Correct answer: Ramelteon
Ramelteon mimics the natural hormone melatonin by acting as a selective agonist at MT1 and MT2 receptors in the suprachiasmatic nucleus. It has no affinity for GABA receptors and carries a lower risk for abuse or dependence.
Keep practicing
More Sedatives and Hypnotics questions
- Suvorexant represents a newer class of hypnotics that works by which mechanism?
- Which benzodiazepine is preferred for use in elderly patients or those with liver failure because it undergoes only Phase II conjugation?
- What is the primary clinical use of the ultra-short-acting barbiturate Thiopental?
- Buspirone is unique among anxiolytics because it:
- Which benzodiazepine has an exceptionally short half-life and is frequently used for procedural sedation?
- What is the phenomenon called when a patient requires larger doses of a sedative to achieve the same effect after prolonged use?